Table III. Univariate analysis of factors predicting CNS involvement in patients with AML.

Factor	Odds ratio* (95% CI)	P value
LDH >700 IU/L	2.6 (1.4 to 6.9)	<0.003
Percent bone marrow blasts	2.7 (1.2 to 6.5)	0.002
Monoblastic subtype (FAB-M5)	2.8 (1.4-5.8)	0.004
Mutations
Flt3	2.2 (1.1-4.7)	0.03
Nuclophosmins1	1.7 (0.6-4.8)	0.3
Age <50	2.0 (1.0 to 2.7)	0.03
Albumin	NA	0.06
Sex	NA	0.4
Complete blood cell counts
Hemoglobin	NA	0.8
White blood cell	NA	0.1
Platelets	NA	0.5

^*Odds ratio for categorical variables is based on the exp(β) of the logistic regression model. CI, confidence interval; NA ,not applicable.