Table 2.
HRQOL in Survivors With Pulmonary Dysfunction Compared With Survivors Without Pulmonary Dysfunction and Controls
| SF-36 Domains | Survivors With Pulmonary Dysfunction* (n = 54) |
Survivors Without Pulmonary Dysfunction (n = 62) |
Controls (n = 39) |
P | |||
|---|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | Mean | SD | ||
| General health | 52.3 | 21.4 | 59.1 | 22.3 | 77.9 | 16.4 | < .01 |
| Physical functioning | 71.3 | 27.2 | 87.4 | 17.9 | 96.2 | 9.7 | < .01 |
| Role limitations due to physical health | 69.9 | 35.1 | 87.7 | 22.3 | 95.4 | 17.3 | < .01 |
| Role limitations due to emotional problems | 73.8 | 43.0 | 80.0 | 35.8 | 99.1 | 5.3 | < .01 |
| Low energy/increased fatigue | 48.2 | 24.8 | 57.1 | 23.0 | 64.9 | 17.4 | < .01 |
| Emotional well-being | 67.5 | 22.4 | 71.1 | 19.9 | 80.3 | 12.1 | < .01 |
| Social functioning | 75.9 | 25.4 | 81.9 | 23.6 | 96.0 | 7.7 | < .01 |
| Pain | 73.2 | 27.0 | 82.3 | 18.4 | 91.6 | 11.4 | < .01 |
NOTE. Analysis was limited to symptomatic childhood cancer survivors (n = 116) and healthy controls (n = 39) who were age18 years or older at study enrollment.
Abbreviations: HRQOL, health-related quality of life; SF-36, Medical Outcomes Study 36-Item Short-Form Health Survey; SD, standard deviation.
*
Defined as obstructive lung disease, restrictive lung disease, or diffusion capacity abnormality.