Extended Data Figure 2. Expression of TP53 is not associated with its gene copy number.
a, b, Scatterplots of TP53 copy number versus protein expression (a) or mRNA expression (b) in colorectal tumours in TCGA database. Pearson correlation coefficient (r) and p value are displayed. c, Relative mRNA expression of TP53 in human CRC cell lines (normalized to that in HCT116 cell line). Data are mean and s.d. of three independent experiments.