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. 2015 Apr 20;2015:248264. doi: 10.1155/2015/248264

Table 2.

Univariate and multivariate analysis of the variables significantly associated with severe GvHD.

aGvHD n with outcome/n with variant n with outcome/n without variant Univariate Multivariate
ODDS ratio CI 95% P ODDS ratio CI 95% P
IL10-1082GG
DNR
II–IV 12/16 (75.0%) 33/85 (38.8%) 3.77 1.33–12.0 0.012 4.50 1.45–16.58 0.008
III-IV 4/16 (25.0%) 7/85 (8.2%) 4.21 1.17–14.65 0.029 5.15 0.95–30.15 0.057

FAS-670CC + CT
DNR
II–IV 38/74 (52.3%) 7/27 (25.9%) 2.81 1.12–7.65 0.027 2.90 1.11–8.35 0.029
III-IV 11/74 (14.9%) 0/27 (0%) 9.81 1.20–1274 0.029 ns

TLR4-3612TT
DNR
III-IV 11/51 (21.6%) 2/56 (3.4%) 6.82 1.88–36.47 0.002 12.86 2.47–138.8 0.001

IL18-607TT + TG
PT
II–IV 39/77 (50.6%) 7/30 (23.3%) 3.08 1.25–8.31 0.014 ns

SSC III-IV 3.83 1.25–8.51 0.003 6.20 1.40–32.31 0.016

DNR: donor; PT: patient; SSC: source of stem cells; ns: not significant.