Table 3.
Expression of top EMT-related genes in SEMA6D-H versus L comparison.
| Symbol | Description |
p value (H versus L) |
Fold change | Fold (description) |
|---|---|---|---|---|
| MMP9 | Matrix metallopeptidase 9 (gelatinase B, 92 kDa gelatinase, 92 kDa type IV collagenase) | 0.163673 | −3.61 | H down versus L |
| TMEM132A | Transmembrane protein 132A | 5.87E − 27 | −2.21 | H down versus L |
| BMP7 | Bone Morphogenetic Protein 7 | 2.85E − 05 | −1.79 | H down versus L |
| DSC2 | Desmocollin 2 | 8.55E − 07 | −1.74 | H down versus L |
| HPRT1 | Hypoxanthine phosphoribosyltransferase 1 | 7.82E − 46 | −1.72 | H down versus L |
| KRT19 | Keratin 19 | 1.44E − 15 | −1.64 | H down versus L |
| SPP1 | Secreted phosphoprotein 1 | 0.000141 | −1.55 | H down versus L |
| PPPDE2 | PPPDE peptidase domain containing 2 | 6.02E − 24 | −1.48 | H down versus L |
| KRT7 | Keratin 7 | 1.51E − 06 | −1.48 | H down versus L |
| CDH1 | Cadherin 1, type 1, E-cadherin (epithelial) | 9.38E − 11 | −1.46 | H down versus L |
| COL3A1 | Collagen, type III, alpha 1 | 2.53E − 15 | 1.89 | H up versus L |
| MMP2 | Matrix metallopeptidase 2 (gelatinase A, 72 kDa gelatinase, 72 kDa type IV collagenase) | 3.74E − 25 | 1.97 | H up versus L |
| SNAI2 | Snail homolog 2 (Drosophila) | 8.28E − 24 | 2.08 | H up versus L |
| MITF | Microphthalmia-associated transcription factor | 1.33E − 42 | 2.08 | H up versus L |
| TCF4 | Transcription factor 4 | 2.17E − 75 | 2.35 | H up versus L |
| AHNAK | AHNAK nucleoprotein | 5.98E − 57 | 2.37 | H up versus L |
| ZEB2 | Zinc finger E-box binding homeobox 2 | 1.55E − 44 | 2.51 | H up versus L |
| ZEB1 | Zinc finger E-box binding homeobox 1 | 2.14E − 73 | 2.67 | H up versus L |
| GNG11 | Guanine nucleotide binding protein (G protein), gamma 11 | 1.31E − 54 | 3.30 | H up versus L |