Skip to main content
. 2015 Apr 20;2015:967203. doi: 10.1155/2015/967203

Figure 3.

Figure 3

Amyloid deposits in WT and Tg neocortex. (a) Aβ IHC in 6-, 9-, and 18-month-old WT and Tg neocortex. A stronger staining is consistently present in Tg neurons, compared to WT. At late stages, Aβ accumulates within senile plaques. Scale bars, 40 μm. (b) Immunolocalization of anti-oligo-pyroGlu Aβ, revealing low molecular weight oligomers. The reaction product accumulates in Tg neocortex starting from 9 months and is observed both intra- and extracellularly, particularly inside the plaques. Scale bars, 40 μm.