Table 3.

Changes in Average Hot Flash Frequency and Severity from Baseline to 12 Weeks, by Intervention Assignment

	Paced respiration (N = 62)			Music listening (N = 61)			Between-group difference in 12-week change
	Baseline	12-Week*	Change (95%CI)	Baseline	12-Week*	Change (95%CI)	Diff. (95%CI)	P-value
No. of hot flushes per day	8.6 (±3.7)	6.4 (±4.3)	−1.8 (−2.6 to − 0.9)	8.4 (±3.3)	5.1 (±3.2)	−3.0 (−3.8 to−2.1)	−1.2 (−2.4 to −0.0)	0.048
No. of moderate- to-severe hot flushes per day	5.4 (±3.3)	4.1 (±4.2)	−1.0 (−1.9 to − 0.2)	5.6 (±3.7)	2.6 (±2.4)	−2.4 (−3.2 to − 1.6)	−1.4 (−2.6 to −0.2)	0.02
Total hot flash severity score**	14.9 (±7.6)	11.2 (±9.8)	−3.0 (−4.9 to − 1.2)	15.5 (±8.1)	8.1 (±5.6)	−6.0 (−7.8 to − 4.1)	−2.9 (−5.4 to −.35)	0.023

Data are mean (±SD), or as change (95%CI) unless otherwise specified. Linear mixed models with random intercepts and slopes were used to assess between-group changes in outcomes from baseline to 4 and 12 weeks.

^*12-week data are based on participants with 12 week hot flash diary data (46 and Paced respiration and 48 Music listening).

^**Total hot flash severity scores were calculated by adding the severity scores of all hot flushes reported over a 7-day period.