Table 3.
Clinical sensitivity and prevalence for UCP-LF assays and KK analysis
| Kisumu set: N = 113 | True positives a | False negatives b | Sensitivity | Prevalence |
|---|---|---|---|---|
| Gold Standard | 48 | 0 | 100% | 42% |
| UCAA10 | 21 | 27 | 44% | 19% |
| UCAA250 | 30 | 18 | 63% | 27% |
| UCAA2000 | 47c | 1 | 98% | 42% |
| KK1-2 | 17 | 31 | 35% | 15% |
| KK3-4 | 13 | 35 | 27% | 12% |
| KK5-6 | 11 | 37 | 23% | 10% |
| KK1-6 | 25 | 23 | 52% | 22% |
aThe Gold Standard positive is defined as a sample (stool or paired urine) with at least a single egg in the 6-fold KK stool analysis or a CAA level > 0.3 pg/mL in urine as determined with the UCAA2000 assay.
bFalse negatives are defined against the Gold Standard and calculated by ‘False Negatives = 48 – True Positives’.
cNumber of UCAA2000 positives (including 16 additional positives, Figure 4).