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Sanger sequencing evaluation of APC SNPs in gDNA and RNA of affected and unaffected individuals
| Subject | |||||
|---|---|---|---|---|---|
| 0124 (III-5) | 0124 (III-4) | 0130 (IV-1) | 0163 (III-2) | ||
| SNP | Affected | Unaffected | Affected | Affected | |
| rs459552 | gDNA | A/T | -/- | A/T | A/T |
| cDNA | A/A | -/- | A/A | A/A | |
| rs465899 | gDNA | A/G | A/G | -/- | A/G |
| cDNA | A/A | A/G | -/- | A/A | |
Sequences which are heterozygous are denoted in bold.
cDNA, complementary DNA; gDNA, genomic DNA.
