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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Toxicol Appl Pharmacol. 2014 Sep 22;281(2):174–184. doi: 10.1016/j.taap.2014.08.027

Figure 7. Mitochondrial and cytosolic fraction CPS-1 expression 4 h following APAP overdose.

Figure 7

Treatment groups were as described in Figure 1. Panel A contains the densitometry for mitochondrial and cytosolic CPS-1 Western blots. Panel B depicts mitochondrial (upper gel) and cytosolic (lower gel) probed for CPS-1. Panel C denotes 4-HNE binding of western blot band which was positive for CPS-1. The upper row depicts mitochondria and the lower bands depict cytosolic. Panel D depicts densitometry analysis for cytosolic 4-HNE adduction. Densitometry was normalized to total protein lane staining. Panel E depicts cytosolic protein gel staining. Values represent mean ± S.E.M. with n=3-5 mice per group. Groups with a different superscript letter (a, b or c) are statistically different (p<0.05).