Table 1.
Group demographics and clinical characteristics
| HC | PD | Group Difference (p) | |
|---|---|---|---|
| Number of tractography | 27 | 50 | — |
| Age (years) | 56.8 ± 10.7 | 59.7 ± 9.2 | n.s. |
| Sex (M / F) | 21 / 6 | 32 / 18 | n.s. |
| Handedness (L:R:M)(a) | 23 : 4 : 0 | 44 : 4 : 2 | — |
| Side of symptom onset (L:R:S)(b) | — | 27 : 22 : 1 | — |
| Total UPDRS (I–IV)(c) | 5.8 ± 2.5 | 38.8 ± 13.3 | <0.001 |
| UPDRS III(d) | 0.4 ± 0.8 | 21.9 ± 7.8 | <0.001 |
| Hoehn & Yahr(e) | 0 | 1.6 ± 0.5 | <0.001 |
| MoCA(f) | 28.1 ± 1.1 | 28.0 ± 1.7 | n.s. |
| Putaminal DAT (minimum side) | 1.25 ± 0.4 | 0.58 ± 0.2 | <0.001 |
(a)
L:R:M = Left : Right : Mixed handedness
(b)
L:R:S = Left : Right : Symmetric onset
(c)
Unified Parkinson’s Disease Rating Scale (Movement Disorder Society revision) Part I-IV, range 0 to 200
(d)
Unified Parkinson’s Disease Rating Scale Part III, range 0 to 72
(e)
Hoehn and Yahr scale, range 0 to 5
(f)
MoCA: Montreal Cognitive Assessment test, range 0 to 30