. Author manuscript; available in PMC: 2016 Jan 1.

Published in final edited form as: J Appl Toxicol. 2015 Apr 29;36(1):161–174. doi: 10.1002/jat.3157

Table 2.

mRNA and miRNA in MC− Air mice developing lung pathology (pathology control mice) significantly up-or down-regulated when compared to MC− Air mice with normal lung tissue (normal control mice).

	mRNA	miRNA

Hyperplasia		Up-regulated: miR-340-5p
Fibrosis	Up-regulated: 17200163	Up-regulated: miR-200c-3p, miR-26b-5p, miR-702-5p, miR-30a-3p, miR-140-5p, miR-146a-5p, miR-151-5p, miR-27b-3p, miR-425-5p, miR-192-5p, miR-194-5p
	Down-regulated: Rhox3h
		Down-regulated: miR-345-5p, miR-145a-5p, miR-29c-3p, miR425-3p, miR-6240, miR-122-5p, miR-10a-5p, miR-326-3p, miR-339-5p, miR-378a-5p
Bronchiolo-alveolar Adenoma	Up-regulated: 17200713, 17460573, A230057D06Rik, Rhox2g	Up-regulated: miR-466c-5p
Bronchiolo-alveolar Adenoma		Down-regulated: miR-690, miR-29b-3p, miR-497-5p, miR-425-3p, miR-500-3p, miR-345-5p, miR-144-3p, miR-5112
Bronchiolo-alveolar Adenocarcinoma	Up-regulated: 17225809, 17313575, 17448801	Down-regulated: miR-345-5p, miR-144-3p, miR-130a-3p, miR-19a-3p, miR-29b-3p, miR-19b-3p, miR-362-5p, miR-497-5p
Bronchiolo-alveolar Adenocarcinoma	Down-regulated: cc119