Table 1.
Patients characteristics
| Variable | All (n=330) | Intensive (n=197) |
Non-intensive (n=133) |
P-Value |
|---|---|---|---|---|
| Age (SD) | 69.9 (6.8) | 66.3 (4.6) | 75.2 (6.2) | < 0.0001 |
| Male gender (%) | 195 (59.1%) | 110 (55.8%) | 85 (63.9%) | 0.14 |
| White Race (%) | 321 (97.3%) | 190 (96.4%) | 131 (98.5%) | 0.47 |
| Marital Status (%) | 0.05 | |||
| Single | 36 (10.9%) | 22 (11.2%) | 14 (10.5%) | |
| Married | 243 (73.6%) | 147 (74.6%) | 96 (72.2%) | |
| Divorced | 26 (7.9%) | 19 (9.6%) | 7 (5.3%) | |
| Widow | 25 (7.6%) | 9 (4.6%) | 16 (12.0%) | |
| Education (%) | 0.04 | |||
| High school or less | 136 (41.2%) | 75 (38.1%) | 61 (45.9%) | |
| College | 150 (45.5%) | 86 (43.7%) | 64 (48.1%) | |
| Post-Grad | 44 (13.3%) | 36 (18.3%) | 8 (6.0%) | |
| Therapy-related disease? (%) | 48 (14.6%) | 29 (14.7%) | 19 (14.3%) | 0.91 |
| Comorbidity Index (SD) | 1.9 (1.8) | 1.7 (1.6) | 2.2 (2.1) | 0.02 |
| Disease Risk (%) | 0.40 | |||
| Favorable | 25 (7.6%) | 18 (9.1%) | 7 (5.3%) | |
| Intermediate | 165 (50.0%) | 99 (50.3%) | 66 (49.6%) | |
| High Risk | 140 (42.4%) | 80 (24.2%) | 60 (45.1%) | |
| ECOG performance status (SD) | 0.88 (0.56) | 0.77 (0.55) | 1.0 (0.55) | < 0.0001 |
| Achieved complete remission | 171 (51.8%) | 140 (71.1%) | 31 (23.3%) | < 0.0001 |
| Received allogeneic HCT | 109 (33.0%) | 102 (51.8%) | 7 (5.3%) | < 0.0001 |
| Median survival in days [95%CI] | 340 [280–391] | 390 [309–487] | 255 [198–354] | < 0.0001 |
SD = Standard deviation; ECOG = Eastern Cooperative Oncology Group; HCT = Hematopoietic Stem Cell Transplantation.