Table 1.
Baseline characteristics
| GOLD A (n = 27) | GOLD B (n = 91) | GOLD C (n = 17) | GOLD D (n = 191) | |
|---|---|---|---|---|
| Age, yr | 65.9 (7.5) | 66.6 (8.8) | 68.4 (10.2) | 65.7 (8.0) |
| Male, n (%) | 21 (78) | 58 (64) | 11 (65) | 109 (57) |
| White, n (%) | 26 (96) | 85 (93) | 15 (88) | 159 (83) |
| Smoking status, n (%) | ||||
| Current | 4 (15) | 16 (18) | 2 (12) | 36 (19) |
| Ever | 26 (96) | 88 (97) | 17 (100) | 177 (93) |
| Duration of COPD,* yr | 3.5 (3.3) | 5.0 (3.7) | 4.8 (3.2) | 6.8 (3.8) |
| FEV1, L | 2.03 (0.5) | 1.85 (0.5) | 1.19 (0.4) | 1.3 (0.4) |
| FEV1, % predicted | 64.7 (11.0) | 62.2 (8.8) | 40.1 (9.9) | 35.0 (10.9) |
| FEV1/FVC | 0.58 (0.10) | 0.60 (0.11) | 0.43 (0.12) | 0.45 (0.14) |
| 6MWD,* m | 472 (75) | 392 (105) | 435 (79) | 313 (102) |
| Accelerometry | ||||
| Total steps* | 6,791 (3,567) | 4,216 (2,729) | 5,456 (3,132) | 3,247 (2,634) |
| Supplemental oxygen use,* n (%) | 2 (7) | 14 (15) | 5 (29) | 98 (51) |
| Pulmonary rehab during study, n (%) | 2 (4) | 8 (9) | 2 (12) | 33 (17) |
| Exacerbations in prior yr, n | ||||
| 0 | 27 | 91 | 15 | 141 |
| 1–2 | 0 | 0 | 2 | 41 |
| ≥3 | 0 | 0 | 0 | 9 |
Definition of abbreviations: 6MWD = 6-minute-walk distance; COPD = chronic obstructive pulmonary disease; GOLD = Global Initiative for Chronic Obstructive Lung Disease.
Values given as mean (SD) unless otherwise noted.
*
P < 0.05 for differences across GOLD 2011 groups by one-way analysis of variance.