Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Mar 4;17(4):405–415. doi: 10.1002/ejhf.244

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2015 The Authors. European Journal of Heart Failure published by John Wiley & Sons Ltd on behalf of European Society of Cardiology.

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

PMC Copyright notice

Receiver operating characteristic (ROC) analysis for the use of microRNAs (miRNAs) to improve the diagnostic utility of BNP in the differentiation of heart failure with preserved ejection fraction (HFpEF) from heart failure with reduced ejection fraction (HFrEF). ROC analysis highlights that the diagnostic value of using miRNA combinations to differentiate HFpEF from HFrEF is superior to using BNP on its own. The best diagnostic test includes BNP with a combination of four miRNAs, namely miR-328, miR-30c, miR-221, and miR-375, with an area under the curve (AUC) of 0.854.