Table 1.
Tumor number in Apc+/580S,Kras+/LSL, CAC+ mice.
| Mouse ID |
Sex | Age at Death (wk) |
Cause of death | Number Macroscopic tumors in entire tissue |
Number Microscopic tumors in one tissue section |
|||||
|---|---|---|---|---|---|---|---|---|---|---|
| SI | Cecum | CR | SI | Cecum | CR | |||||
| 460 | F | 6 | Euthanized- 6 wk time point | 0 | 0 | 1 | 0 | 0 | 0 | |
| 281 | M | 7.5 | Euthanized- anal prolapse | 0 | 0 | 1 | 0 | 0 | 1 | |
| 235 | M | 11 | Euthanized-distended anal region | 0 | 0 | 5 | 0 | 0 | 4 | |
| 236 | M | 11 | Euthanized-distended anal region | 0 | 0 | 9 | 0 | 0 | 2 | |
| 158 | F | 14.5 | Euthanized- anal prolapse | 0 | 0 | 3 | 0 | 0 | 3 | |
| 154 | M | 15 | Found dead | - | 0 | 3 | - | - | - | |
| 159 | F | 15 | Euthanized- 15 wk time point | 0 | 0 | 3 | 0 | 0 | 1 | |
| 180 | F | 16 | Euthanized- lethargy | 0 | 0 | 4 | 0 | 2 | 1 | |
| 189 | F | 16 | Euthanized- anal prolapse | 0 | 0 | 5 | 0 | 0 | 1 | |
| 147 | M | 21 | Euthanized- weight loss | 0 | 0 | 5 | 0 | 1 | 2 | |
| 228 | M | 15 | Euthanized -anal prolapse | 0 | 0 | 8 | 0 | 0 | 5 | |
| Average | 4.6 | 2.2 | ||||||||
SI, small intestine; CR, colorectum; F, female; M, male. Macroscopic tumors were detected from the entire tissue under a dissecting microscope. Microscopic tissues were detected in one cross-section cut from a SI or CR swiss roll or a section from the center of the cecum.