Fig. 5. CXCR4 blockage does not alter neutrophil recruitment.
In vivo chemokinesis assay in LDLr−/− mice, transplanted with either bone marrow infected with LV.Empty or LV.CXCR4deg A, Percentage of peritoneal Ly6GhighCD11b+(CD71−) neutrophils at 2 h after KC injection. ***P < 0.001 compared to T = 0. B, Percentage of recruited neutrophils in response to SDF-1α. *P < 0.05 compared to T = 0, #P < 0.05 compared to LV.Empty. C, Percentage of peritoneal neutrophils in response to 3% Brewer’s Thioglycollate in control versus AMD3100 treated mice.