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. Author manuscript; available in PMC: 2015 May 4.
Published in final edited form as: Sci Signal. 2015 Apr 21;8(373):ra37. doi: 10.1126/scisignal.2005846

Fig. 7. O2 sensing in the carotid body.

Fig. 7

Schematic presentation of the signaling pathways associated with the interplay between three gases—O2, CO, and H2S—in glomus cells of the carotid body (CB) and their impact on CB neural activity and breathing. Cys265 and Cys282 are located in the heme regulatory motif of HO-2. Ser377 is the target residue in the putative PKG recognition sequence in CSE.