Skip to main content
. Author manuscript; available in PMC: 2015 May 4.
Published in final edited form as: Biochim Biophys Acta. 2015 Feb 4;1852(5):882–892. doi: 10.1016/j.bbadis.2015.01.019

Fig. 9.

Fig. 9

Effects of calpastatin over-expression on ER stress in an in vivo mouse model of ischemia/reperfusion (I/R). Adult transgenic mice with calpastatin over-expression (Tg-CAST) and their wild-type littermates (WT) were subjected to an I/R procedure. (A) Calpain activity was measured in heart tissue lysates. Data are mean ± SD, n = 6. *P < 0.05 vs Sham. (B) Representative western blots for ER stress markers from 2 out of 6 hearts in each group. (C–F) Quantifications for GRP78 (C), CHOP (D), phosphorylated JNK1/JNK1 (E) and phosphor-ylated JNK2/JNK2 (F). Data are mean ± SD, n = 6. *P < 0.05 vs Sham + WT and #P < 0.05 vs I/R + WT.