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. Author manuscript; available in PMC: 2015 May 4.
Published in final edited form as: Depress Anxiety. 2014 Apr 17;31(10):805–813. doi: 10.1002/da.22271

Figure 2.

Figure 2

Regions where anhedonic depression or anxious arousal moderated coupling with dorsolateral prefrontal cortex. The axial slice above left (z = −12) displays the two clusters in orbitofrontal cortex (OFC) exhibiting condition-dependent connectivity that was moderated by anhedonic depression. Specifically, depression was associated with decreased coupling between left dorsolateral prefrontal cortex (associated with approach motivation) and the blue/green OFC cluster. In contrast, depression was associated with increased coupling between right dorsolateral prefrontal cortex (associated with avoidance motivation) and the red/yellow cluster. The coronal slice above right (y = 3) displays the amygdala cluster exhibiting condition-dependent connectivity that was moderated by anxious arousal. Specifically, anxious arousal was associated with increased coupling between right dorsolateral prefrontal cortex (associated with avoidance motivation) and the red/yellow amygdala cluster.