Table 1. Severe Pain by Selected Characteristics^*.

	ORAL N= 1196		PHARYNX N= 696		LARYNX N= 448
Variable	No/Yes	P	No/Yes	P	No/Yes	P
All individuals	952/244		565/131		376/72
TNM Classification
Tumor
0-2	557/87	<0.001	303/32	<0.001	189/22	0.001
3-4	343/147		251/90		176/49
Node
0	356/78	NS	107/28	NS	223/39	NS
1	120/44		76/13		33/12
2	176/48		126/25		58/16
3	37/10		36/16		14/2
Metastasis
Non-metastatic	891/233	NS	545/116	0.010	360/70	NS
Metastatic	8/2		8/7		5/0
Comorbidities
Heart No	783/186	0.035	480/99	0.013	298/61	NS
Yes	169/58		85/32		78/11
Lung No	871/213	0.049	528/109	<0.001	321/51	0.005
Yes	81/31		37/22		55/21
Hypertension No	567/145	NS	351/78	NS	196/33	NS
Yes	385/99		214/53		180/39
Stroke No	918/232	NS	541/120	NS	356/70	NS
Yes	34/12		24/11		20/2
Diabetes No	836/208	0.282	507/109	0.047	332/60	NS
Yes	116/36		58/22		44/12
Behavioral Factors
Alcohol Never	296/79	<0.001	134/21	<0.001	92/23	NS
Social	323/47		188/19		103/14
Moderate	119/24		81/20		48/6
Heavy	142/70		131/56		106/24
Smoking Never	378/71	<0.001	172/15	<0.001	44/1	0.003
Yes, but quit	412/90		263/59		208/35
Yes, current	157/83		126/57		123/36
Sociodemographic
Age <50	183/60	NS	107/28	NS	56/15	NS
≥50	769/184		458/103		320/57
Male	704/165	0.053	455/111	NS	301/52	NS
Female	248/79		110/20		75/20
Non-Hispanic White	778/171	<0.001	487/95	<0.001	277/51	0.020
Hispanics	78/34		35/14		44/3
Non-Hispanic Blacks	33/23		21/18		42/15
Symptoms
Depressed Mood	838/175	<0.001	498/88	<0.001	310/56	NS
None-moderate	48/49		35/31		31/11
Severe
Fatigue
None-Moderate	662/88	<0.001	410/45	<0.001	245/17	<0.001
Severe	201/120		105/68		92/47
WHO Ladder
None	696/139	<0.001	430/76	<0.001	283/40	<0.001
Level 1	110/19		47/11		38/8
Level 2	105/53		64/27		40/9
Level 3	41/33		24/17		15/15

^*Missing data for some variables