Table 2. Predictors of Survival in Patients with HNSCC (Multivariable Analyses).
| Variable | Odds Ratio | 95% CI | p-value | |
|---|---|---|---|---|
|
| ||||
| Lower | Upper | |||
| *Cancer | 0.004 | |||
| Larynx | 1.0 | REF | ||
| Oral | 1.111 | .896 | 1.379 | .337 |
| Pharynx | .719 | .567 | .912 | .007 |
| Symptoms | ||||
| Pain Severity (0-10) | 1.038 | 1.005 | 1.073 | .023 |
| WHO Ladder | ||||
| 0 | 1.0 | REF | 0.286 | |
| 1 | 1.033 | .759 | 1.406 | .835 |
| 2 | .818 | .614 | 1.089 | .169 |
| 3 | 1.215 | .860 | 1.716 | .269 |
| Fatigue severity | ||||
| Non-Severe | 1.0 | REF | ||
| Severe | 1.302 | 1.06 | 1.59 | 0.011 |
| TNM Classification | ||||
| T | ||||
| 0-2 | 1.0 | REF | ||
| 3-4 | 1.646 | 1.355 | 1.999 | <0.001 |
| Node | <0.001 | |||
| 0 | 1.0 | REF | ||
| 1 | 1.117 | .868 | 1.437 | .391 |
| 2 | 1.141 | .905 | 1.437 | .264 |
| 3 | 2.229 | 1.628 | 3.052 | .000 |
| Metastasis | ||||
| Non-metastatic | 1.0 | REF | ||
| Metastatic | 4.220 | 2.525 | 7.052 | .000 |
| Comorbidites | ||||
| Lung diseases | ||||
| No | 1.0 | REF | ||
| Yes | 1.527 | 1.194 | 1.954 | .001 |
| Behavioral Factors | ||||
| Alcohol Intake | 0.077 | |||
| Non-drinker | 1.0 | REF | ||
| Social | .989 | .765 | 1.279 | .933 |
| Moderate | 1.175 | .869 | 1.588 | .294 |
| Heavy | 1.314 | 1.019 | 1.695 | .035 |
| Smoking | <0.001 | |||
| Never | 1.0 | REF | ||
| Yes, but quit | 1.557 | 1.188 | 2.040 | .001 |
| Yes, current | 1.882 | 1.406 | 2.518 | .000 |
| Socio-demographics | ||||
| Race | 0.025 | |||
| NH White | 1.0 | REF | ||
| Hispanics | .950 | .690 | 1.308 | .753 |
| NH Blacks | 1.514 | 1.110 | 2.064 | .009 |
| Age | ||||
| Age <50 | 1.0 | REF | ||
| Age ≥50 | 2.256 | 1.686 | 3.018 | .001 |