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. Author manuscript; available in PMC: 2015 May 4.
Published in final edited form as: Dev Dyn. 2014 Jan 4;243(4):601–611. doi: 10.1002/dvdy.24100

Figure 4. At 1 month, biglycan, decorin, fibromodulin, and lumican were immunolocalized within collagen rich structures including the cardiac valves and arterial walls of the maturing heart.

Figure 4

A–D: Biglycan (green), E–H: decorin (green), I–L: fibromodulin (green) and M–P: lumican (green) immunolocalization. Boxes magnified in adjacent panels and designated with a prime. *-annulus region associated with the anterior cusp (AC) of the pulmonary valve (PV); solid arrows-regions where valve cusps or leaflets anchor into adjacent tissue; solid arrowheads- staining within the cusps or leaflets; open arrowheads- arterial wall staining; LC-left cusp of the PV; RC-right cusp of the PV; RV- right ventricle; PA-pulmonary artery wall; LA-left atrium; RCC- right coronary cusp of the aortic valve (AV); LCC- left coronary cusp of the AV; LV-left ventricle; A-adventitia of aorta; M-medial layer of aorta; MV-mitral valve; AL-anterior leaflet; PL-posterior leaflet; Para- paraformaldehyde fixed tissue; Amst- Amsterdam fixed tissue. Blue- alpha sarcomeric actin; red- propidium iodide. Scale bars: A= 200um, applies to B, D, E, F, H, I, J, L, M, N, P; B′= 50um, applies to B″, C, F′, F″, G, J′, J″, K, N′, N″, O.