Table 1.

Comparison of adducts formed by reaction of E₂-3,4-Q with dG, Guo, ds-DNA, ss-DNA, or t-RNA

	Adducts, µmol/mol DNA-P
	dGa	Guoa	ds-DNAb		ss-DNAb		t-RNAb
Time	N7Gua	N7Gua	N3Ade	N7Gua	N3Ade	N7Gua	N3Ade	N7Gua
10 h	80	5	123	135	21.2	23.4	<0.7	<0.7
1 day	100	14	131	138	19.8	20.7	2.9	2.5
2 days		22					4.9	4.7
5 days		38					7.0	7.3
10 days		62					9.2	8.4

^aReaction at room temperature, pH 4.0.

^bReaction at 37 °C, pH 7.0.