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. 2015 Mar-Apr;20(2):76–89. doi: 10.5863/1551-6776-20.2.76

Figure 1.

Figure 1.

Pre and post inhibitory neuron in neonatal and mature brain. GABA neurotransmitter effect based on Cl- gradient in post-synaptic neuron. Mechanism of action of common antiepileptics depicted. Inline graphic KCC2; Inline graphic NKCC1

GABA, gamma-Aminobutyric acid; KCC2, Potassium-chloride transporter member 5; NKCC1, Na-K-Cl cotransporter