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. 2015 May 4;10(5):e0125625. doi: 10.1371/journal.pone.0125625

Fig 2. CSCs display cell-autonomous resistance to chemotherapy.

Fig 2

(A, B) Cell death analysis of CSCs and non-CSCs from XhCRC or SW620 cells was assessed by CCK-8 activity assay upon chemotherapeutic treatment (5-Fu or OXA).**P< 0.01, ***P< 0.001. (C, D) Enrichment of CSCs in bulk cells from XhCRC (C) and SW620 cells (D) was assessed by FACS analysis based on CD133 expression upon chemotherapy. (E, F) Sphere-forming capacity of bulk cells (XhCRC or SW620 cells) pre-treated by chemotherapeutic agents or DMSO (Ctrl). **P< 0.01, ***P< 0.001.