Table 2. Parameters of insulin action and secretion in ZLR and ZFR groups.
ZLR | S I | Φ 1 | Φ 2 | Φ ss |
---|---|---|---|---|
1 | 10.7 (15.3) | 194 (14.7) | 1.35 (33.3) | 6.98 |
2 | 6.99 (11.4) | 197 (14.3) | 1.72 (29.7) | 5.20 |
3 | 4.19 (25.3) | 121 (21.6) | 1.44 (33.5) | 3.74 |
4 | 10.6 (29.7) | 157 (14.8) | 1.49 (30.7) | 6.90 |
5 | 9.83 (8.6) | 147 (12.8) | 1.77 (29.3) | 7.27 |
6 | 10.0 (14.8) | 233 (29.0) | 1.50 (29.3) | 14.6 |
7 | 10.5 (16.1) | 210 (17.6) | 1.58 (32.3) | 12.2 |
ZFR | S I | Φ 1 | Φ 2 | Φ ss |
1 | 1.6 (17.5) | 268 (6.8) | 7.40 (20.8) | 18.9 |
2 | 0.91 (4.0) | 295 (8.8) | 9.97 (22.5) | 58.3 |
3 | 0.12 (77.0) | 454 (20.3) | 7.80 (30.4) | 91.5 |
4 | 0.45 (22.2) | 363 (19.9) | 7.38 (33.5) | 101 |
5 | 2.54 (16.6) | 376 (20.1) | 7.47 (33.1) | 138 |
6 | 1.47 (30.4) | 411 (19.5) | 7.59 (32.5) | 118 |
7 | 0.95 (5.3) | 556 (17.7) | 8.58 (28.8) | 58.6 |
S I (10-4 dL·kg-1·min-1 /(μU·mL-1)), whole-body insulin sensitivity; Φ 1((pmol/L C-peptide)/(mmol/L glucose)), first-phase responsiveness index; Φ 2 (10-1 min-2·(pmol/L C-peptide)/(mmol/L glucose)), second-phase responsiveness index; Φ ss (min-1·(pmol/L C-peptide)/(mmol/L glucose)), steady-state responsiveness index. All the parameters and indexes were estimated or computed by CPMM and IVGTT, except for S I, which was estimated by GKMM and IVGTT. The percent coefficient of variation of the estimates (CV%) was given in parentheses, when available.