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. 2015 May 4;10(5):e0125252. doi: 10.1371/journal.pone.0125252

Table 2. Parameters of insulin action and secretion in ZLR and ZFR groups.

ZLR S I Φ 1 Φ 2 Φ ss
1 10.7 (15.3) 194 (14.7) 1.35 (33.3) 6.98
2 6.99 (11.4) 197 (14.3) 1.72 (29.7) 5.20
3 4.19 (25.3) 121 (21.6) 1.44 (33.5) 3.74
4 10.6 (29.7) 157 (14.8) 1.49 (30.7) 6.90
5 9.83 (8.6) 147 (12.8) 1.77 (29.3) 7.27
6 10.0 (14.8) 233 (29.0) 1.50 (29.3) 14.6
7 10.5 (16.1) 210 (17.6) 1.58 (32.3) 12.2
ZFR S I Φ 1 Φ 2 Φ ss
1 1.6 (17.5) 268 (6.8) 7.40 (20.8) 18.9
2 0.91 (4.0) 295 (8.8) 9.97 (22.5) 58.3
3 0.12 (77.0) 454 (20.3) 7.80 (30.4) 91.5
4 0.45 (22.2) 363 (19.9) 7.38 (33.5) 101
5 2.54 (16.6) 376 (20.1) 7.47 (33.1) 138
6 1.47 (30.4) 411 (19.5) 7.59 (32.5) 118
7 0.95 (5.3) 556 (17.7) 8.58 (28.8) 58.6

S I (10-4 dL·kg-1·min-1 /(μU·mL-1)), whole-body insulin sensitivity; Φ 1((pmol/L C-peptide)/(mmol/L glucose)), first-phase responsiveness index; Φ 2 (10-1 min-2·(pmol/L C-peptide)/(mmol/L glucose)), second-phase responsiveness index; Φ ss (min-1·(pmol/L C-peptide)/(mmol/L glucose)), steady-state responsiveness index. All the parameters and indexes were estimated or computed by CPMM and IVGTT, except for S I, which was estimated by GKMM and IVGTT. The percent coefficient of variation of the estimates (CV%) was given in parentheses, when available.