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. 2015 May 4;10(5):e0126217. doi: 10.1371/journal.pone.0126217

Fig 11. Illustration of the signaling pathway involved in the effect of HYS-32 on microtubule catastrophes in rat astrocytes.

Fig 11

HYS-32 induces microtubule catastrophes by causing EB1 dislodgement from microtubule plus ends and EB1 accumulation on the microtubule lattice through the modulation of the PI3K-GSK3β signaling pathway.