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aSMase (5A) and nSMase (5B) activities were measured in CSF using fluorescent assays. The data are expressed as the mean ± SEM of the relative fluorescent unit (RFU) per minute using 10 μg protein per assay for CN (n = 70), MCI (n = 40), and AD (n = 29). The asterisk (*) denotes values of P < 0.05 compared with CN.
