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. 2015 May 4;10(5):e0126267. doi: 10.1371/journal.pone.0126267

Fig 3. Intervention Impacts.

Fig 3

Impact of each intervention implemented by itself on (A) total TB cases averted, (B) HIV infections averted, (C) drug susceptible TB cases averted, (D) MDR-TB cases averted, (E) XDR-TB cases averted, and (F) TB and HIV deaths averted over 10 years. XPT: replacement of sputum smear with GeneXpert for baseline microbiologic TB detection. DCT: MDR-TB treatment decentralization, corresponding to new South African guidelines for MDR-TB care. CR: increased cure rate of first-line treatment to 85% for drug susceptible TB, corresponding to WHO goals. IPT: 36 months of IPT for all TST+ HIV+ individuals on ART and 12 mo. for all TST- HIV+ individuals on ART, corresponding to anticipated implementation of new South African guidelines. ART: increasing rate of ART initiation by 24% annually, culminating in the South African goal of 80% ART coverage by 2016. CICF: annual frequency for TB and HIV screening program CICF.