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. 2015 May 4;10(5):e0125111. doi: 10.1371/journal.pone.0125111

Fig 2. P2X7 and P2X4 antagonists block high glucose and palmitate-induced expression of inflammatory genes.

Fig 2

qRT-PCR analysis shows high glucose and palmitate-induced (24 h) transcript levels of CASP1 (A), IL-1β (B), IL-6 (C), PTGS2 (D), and IL-8 (E) in the presence or absence of the P2X7 (AZ11645373) and P2X4 (PSB-12253) antagonists. The transcript levels were normalized to the housekeeping gene, PPIA. n = 3 to 4 independent experiments each done in replicates; *p ≤ 0.05.