Table 3. Adjusted Hazard Ratios 1 for CVD Hospitalisation in Adulthood in Relation to Specific Clinical Category of Infection-Related Childhood Hospitalisations.
Infection subgroup | Cases% [n] (631) | Controls% [n] (6310) | HR 1 , 2 | 95%CI | P-value |
---|---|---|---|---|---|
Lower respiratory tract infection | |||||
0 | 90.0 [568] | 94.9 [5990] | |||
1 | 7.0 [44] | 4.1 [260] | 1.17 | 0.9–1.6 | 0.33 |
2+ | 3.0 [19] | 1.0 [60] | 1.50 | 0.93–2.4 | 0.10 |
Gastro-intestinal infection | |||||
0 | 81.8 [516] | 90.5 [5710] | |||
1 | 10.3 [65] | 7.5 [476] | 0.92 | 0.7–1.2 | 0.57 |
2+ | 7.9 [50] | 2.0 [124] | 1.42 | 1.0–1.9 | 0.03 |
Upper respiratory tract infection | |||||
0 | 78.3 [494] | 88.3 [5574] | |||
1 | 14.7 [93] | 9.2 [582] | 1.42 | 1.1–1.8 | 0.002 |
2+ | 7.0 [44] | 2.5 [154] | 1.65 | 1.2–2.3 | 0.003 |
Urinary tract infection | |||||
0 | 95.10 [600] | 99.0 [6248] | |||
1 | 3.2 [20] | 0.9 [55] | 2.0 | 1.3–3.2 | 0.006 |
2+ | 1.7 [11] | 0.1 [7] | 4.2 | 2.3–7.7 | <0.001 |
Other viral infection | |||||
0 | 88.3 [579] | 95.4 [6017] | |||
1 | 9.8 [45] | 4.2 [266] | 1.35 | 1.0–1.8 | 0.05 |
2+ | 1.9 [7] | 0.4 [27] | 1.55 | 0.7–3.3 | 0.25 |
Skin and soft tissue infection | |||||
0 | 86.9 [548] | 96.6 [6095] | |||
1 | 8.4 [53] | 2.7 [172] | 1.54 | 1.1–2.1 | 0.005 |
2+ | 4.8 [30] | 0.7 [43] | 2.09 | 1.4–3.1 | <0.001 |
1 Hazard ratios are adjusted for year of birth, sex and Indigenous status.
2 Reference group is 0 hospitalisations, for each infection subgroup.