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. 2015 May 4;10(5):e0125342. doi: 10.1371/journal.pone.0125342

Table 3. Adjusted Hazard Ratios 1 for CVD Hospitalisation in Adulthood in Relation to Specific Clinical Category of Infection-Related Childhood Hospitalisations.

Infection subgroup Cases% [n] (631) Controls% [n] (6310) HR 1 , 2 95%CI P-value
Lower respiratory tract infection
 0 90.0 [568] 94.9 [5990]
 1 7.0 [44] 4.1 [260] 1.17 0.9–1.6 0.33
 2+ 3.0 [19] 1.0 [60] 1.50 0.93–2.4 0.10
Gastro-intestinal infection
 0 81.8 [516] 90.5 [5710]
 1 10.3 [65] 7.5 [476] 0.92 0.7–1.2 0.57
 2+ 7.9 [50] 2.0 [124] 1.42 1.0–1.9 0.03
Upper respiratory tract infection
 0 78.3 [494] 88.3 [5574]
 1 14.7 [93] 9.2 [582] 1.42 1.1–1.8 0.002
 2+ 7.0 [44] 2.5 [154] 1.65 1.2–2.3 0.003
Urinary tract infection
 0 95.10 [600] 99.0 [6248]
 1 3.2 [20] 0.9 [55] 2.0 1.3–3.2 0.006
 2+ 1.7 [11] 0.1 [7] 4.2 2.3–7.7 <0.001
Other viral infection
 0 88.3 [579] 95.4 [6017]
 1 9.8 [45] 4.2 [266] 1.35 1.0–1.8 0.05
 2+ 1.9 [7] 0.4 [27] 1.55 0.7–3.3 0.25
Skin and soft tissue infection
 0 86.9 [548] 96.6 [6095]
 1 8.4 [53] 2.7 [172] 1.54 1.1–2.1 0.005
 2+ 4.8 [30] 0.7 [43] 2.09 1.4–3.1 <0.001

1 Hazard ratios are adjusted for year of birth, sex and Indigenous status.

2 Reference group is 0 hospitalisations, for each infection subgroup.