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ECs predict interactions between loops/plugs and the barrel domain. Interactions between the barrel (245–774) and the plug (121–244) domain in FecA are highlighted in the predicted contact map (red, ECs; gray, crystal contacts ≤ 5 Å). Top 10 interdomain contacts between the barrel (red) and the plug domain (pink) are shown on the crystal structure and have a PPV of 0.9.
