Fig. 6.

Glul^fl/fl × Alb-Cre⁺ mice show behavioral abnormalities compared with WT mice. (A and B) Glul^fl/fl and Glul^fl/fl × Alb-Cre⁺ mice were transferred into a light barrier-equipped cage and allowed to adapt to the new environment for 24 h prior to starting the measurement. Total activity time (Left, n = 22 for Glul^fl/fl mice and n = 23 for Glul^fl/fl × Alb-Cre⁺ mice) and counts (Right, n = 23 for Glul^fl/fl mice and n = 24 for Glul^fl/fl × Alb-Cre⁺ mice) (A) and distance traveled (n = 21 for Glul^fl/fl mice and n = 22 for Glul^fl/fl × Alb-Cre⁺ mice) (B) were determined after 24 h. Animals were monitored using the O-Maze test. Time (Left) and visits (Right) in the open arms (C) and time (Left) and visits (Right) in the closed arms (D) are presented (n = 10 for Glul^fl/fl mice and n = 11 for Glul^fl/fl × Alb-Cre⁺ mice).