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. Author manuscript; available in PMC: 2016 May 7.
Published in final edited form as: Nanoscale. 2015 May 7;7(17):7470–7481. doi: 10.1039/c5nr01133g

Figure 2.

Figure 2

Schematic overview of the cell death pathways induced by nAg. At exposure levels impacting cell viability, nAg induces excessive ROS generation that could result in lipid peroxidation on membranes, DNA damage in the nucleus, activation of a mitochondria-dependent apoptosis pathway, and disruption of autophagy flux, which ultimately leads to cell death.