Lethal effects
Sublethal effects
Disruption of energy homeostasis
Induction of proliferation-related genes
Inhibition of RNA transcription
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Deposition in cells and organelles
Physicochemical characteristics of Ag nanoparticles
A combination of Ag ion toxicity and particle effects
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Lethal effects
Sublethal effects
Without significant reduction of cell viability
No obvious ROS generation
Changes in gene and protein expression levels
Disruption in function of crucial proteins
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