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. Author manuscript; available in PMC: 2015 May 4.
Published in final edited form as: Neuropharmacology. 2007 Oct 17;54(2):269–279. doi: 10.1016/j.neuropharm.2007.09.014

Figure 5.

Figure 5

Effects of 0.5 μg (solid) and 5.0 μg (hatched) of intrathecal cytisine administrations on systolic blood pressure, heart rate and nocifensive responses in control (saporin only) and sP-SAP (saporin-substance P conjugate) pretreated rats. All responses denote the maximum response measured during the 10 minute period following administration of each dose of the nicotinic agonist. The second dose of cytisine was administered 30 min following the initial dosing. Each value represents the mean ± SEM. *p<0.05 and **p<0.01 as compared to vehicle-treated rats for the specific dose as determined by two-tailed unpaired Student's t-test.