Table 4.
Univariate and multivariate analysis for overall survival after surgery using Cox relative risk
| Variable |
Univariate analysis |
Multivariate analysis |
||
| RR (95%CI) | P value | RR (95%CI) | P value | |
| PDH expression in tumor (positive vs negative) | 0.552 (0.462-0.658) | < 0.0011 | 0.608 (0.504-0.734) | < 0.0011 |
| PDH expression in NNM (positive vs negative) | 0.830 (0.699-0.987) | 0.035 | 0.869 (0.727-1.039) | 0.123 |
| Age (≥ 60 yr vs < 60 yr) | 1.446 (1.030-2.032) | 0.033 | 1.447 (1.010-2.073) | 0.044 |
| Tumor size (< 4 cm vs ≥ 4 cm) | 2.297 (1.505-3.504) | < 0.0011 | 1.492 (0.956-2.329) | 0.078 |
| Depth of invasion (Tis-1 vs T2-4) | 5.114 (1.889-13.843) | 0.0011 | 1.683 (0.567-4.995) | 0.348 |
| Lauren grade (intestinal-type vs diffuse-type) | 1.978 (1.396-2.803) | < 0.0011 | 1.574 (1.081-2.292) | 0.0181 |
| TNM Stage (0-I vs II-IV) | 1.809 (1.504-2.176) | < 0.0011 | 1.512 (1.191-1.920) | 0.0011 |
| Lymph node metastasis (positive vs negative) | 3.146 (1.989-4.977) | < 0.0011 | 1.733 (1.061-2.830) | 0.0281 |
| Lymphatic invasion (positive vs negative) | 2.041 (1.424-2.924) | < 0.0011 | 1.271 (0.875-1.847) | 0.208 |
| Histological type (differentiated vs undifferentiated) | 1.460 (1.033-2.063) | 0.032 | 1.058 (0.667-1.678) | 0.811 |
1
Significant difference. RR and 95%CI were assessed using univariate and multivariate Cox regression analysis. RR: Relative risk.