Table 3.
SNP | Position on chr 2 (bp/hg19) | Major allele | Minor allele | MAFb | Odds ratio (95 % CI) | P a | R2c | |
---|---|---|---|---|---|---|---|---|
Cases (%) | Controls (%) | |||||||
rs17810398 | 159,660,870 | C | T | 13.3 | 10.5 | 1.314 (1.033–1.680) | 0.027 | Ref. |
rs6146986 | 159,661,997–159,662,874 | – | 878-bp deletion | 13.5 | 10.7 | 1.310 (1.033–1.667) | 0.027 | NA |
rs17810816 | 159,671,992 | A | G | 18.4 | 13.4 | 1.435 (1.163–1.778) | 8.49 × 10−4 | 0.866 |
rs144087548 | 159,718,894 | A | T | 17.4 | 13.8 | 1.296 (1.047–1.609) | 0.018 | 0.735 |
a P from logistic regression adjusted for age and sex
bMAF: minor allele frequency calculated in 710 cases or 612 controls
cR2 to top variant based on CEU samples from the 1,000 genomes project