Table 2.
Estimated mean or rate (95 % CI)a | Effect sizes CBT vs. SRT (95 % CI)b, c | ||
---|---|---|---|
Continued CBT | Sertraline | ||
Primary outcomes | |||
CY-BOCS total scored | 13.64 (10.96–16.32) | 11.65 (7.88–15.42) | −0.29 (−0.85 to −0.27) |
CY-BOCS <16e | 0.50 (0.33–0.67) | 0.45 (0.27–0.65) | 0.10 (−0.72 to 0.52) |
Secondary outcomes | |||
COIS-R parent reportf | 17.20 (11.74–22.67) | 15.50 (8.86–22.14) | −0.11 (−0.67 to 0.45) |
COIS-R child reportf | 15.39 (11.05–19.73) | 8.44 (2.72–14.17) | −0.55 (−1.12 to −0.02) |
CY-BOCS <11g | 0.32 (0.18–0.51) | 0.27 (0.13–0.48) | −0.22 (−0.41 to 0.85) |
30 % reductionh | 0.36 (0.21–0.54) | 0.45 (0.27–0.65) | 0.13 (−0.81 to 0.55) |
aFor CY-BOCS total score and COIS-R estimated mean score at week 30 from the fitted multilevel model. For the responder status, the estimated rate of response at week 30
bFor CY-BOCS total score and COIS-R, between-groups difference in estimated mean score at session 30. For the responder status, between-groups difference in rate at week 30
cNegative effect size suggests that SRT was more effective and positive effect size suggests that continued CBT was more effective
dCY-BOCS total score range from 0 to 40 with larger scores reflecting more OCD symptoms
eCY-BOCS <16 reflects participants that obtained CY-BOCS total score of 15 or below at week 30
fCOIS-R total score range from 0 to 99 with larger scores reflecting more OCD-related functional
g CY-BOCS < 11 reflects participants that obtained CY-BOCS total score of 10 or below at week 30
h30 % reduction of CY-BOCS total score from week 13 to week 30