(b).
| Variables | African American | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Unadjusted OR | 95% C.I. | Pvalue | Adjusted OR | 95% C.I. | P value | ||||
| rs8192678 | TT + CT versus CC | 0.90 | 0.45 | 1.87 | 0.777 | 0.55 | 0.19 | 1.56 | 0.269 |
| rs7656250 | CC + CT versus TT | 0.62 | 0.34 | 1.13 | 0.117 | 1.02 | 0.43 | 2.43 | 0.940 |
| rs4235308 | CC + CT versus TT | 1.29 | 0.75 | 2.21 | 0.356 | 2.53 | 1.08 | 5.92 | 0.028 |
| rs11724367 | CC + CG versus GG | 0.69 | 0.33 | 1.25 | 0.329 | 0.29 | 0.08 | 1.14 | 0.073 |
| rs8192678 ∗ sex | — | — | — | — | — | 1.46 | 0.38 | 5.60 | 0.585 |
| rs7656250 ∗ sex | — | — | — | — | — | 0.36 | 0.11 | 1.13 | 0.079 |
| rs4235308 ∗ sex | — | — | — | — | — | 0.48 | 0.15 | 1.59 | 0.220 |
| rs11724367 ∗ sex | — | — | — | — | — | 3.78 | 0.82 | 17.31 | 0.082 |
Note: the statistically significant results are in bold. Controlled variables included in the logistic regression analysis for adjusted OR were age, sex, BMI, and smoking status. The interactions between sex and individual SNP were also included in logistic regression analysis for all the SNP. P is considered significant at 0.05. OR: odds ratio; CI: confidence interval; PPARGC1A: peroxisome proliferator activated receptor, gamma, coactivator 1 alpha.