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. 2015 May;185(5):1344–1360. doi: 10.1016/j.ajpath.2015.01.024

Figure 4.

Figure 4

Radiculitis in Bb-inoculated rhesus macaques. Inflammatory lesions observed by H&E histopathologic evaluation of spinal nerve roots and DRG at necropsy of animals that received an intrathecal inoculation of live Bb alone and animals inoculated with Bb and treated with Mel, showing radiculitis in the dorsal root of the cervical spinal cord at C7 with Bb alone at 8 weeks (A), in the ventral spinal root (B), DRG inflammation of the C6 cervical region with Bb alone at 14 weeks (C), DRG neuritis as seen in the nerve adjacent to the C8 cervical DRG with Bb alone at 8 weeks (D), radiculitis in the dorsal root of the cervical spinal cord at C7 with Bb+Mel at 8 weeks (E), and the absence of inflammatory lesions in the DRG and dorsal root of the C8 cervical region with Bb+Dex at 8 weeks (F). Scale bar = 50 μm. Bb, Borrelia burgdorferi; Dex, dexamethasone; DRG, dorsal root ganglia; H&E, hematoxylin and eosin; Mel, meloxicam.