Table 2.
F-Wave Latencies Recorded for Motor Nerves (Median, Ulnar, and Tibial) in Rhesus Macaques Inoculated Intrathecally with Live Bb and Left Untreated or Treated with Either Dex or Mel
| Rhesus macaques and treatment | F-wave latencies (msec) |
|---|---|
| GN22 (Bb alone 8 weeks) | Abnormal F waves in all nerves recorded from week 2 PI until end of study Median F waves = 14.8–20.2 (UL 14.7)∗ Ulnar F waves = 15.1–22.5 (UL 14.8)∗ Tibial F waves = 21.2–30.1 (UL 20.7)∗ |
| GB09 (Bb+Dex 8 weeks) | Normal |
| GP33 (Bb+Mel 8 weeks) | Normal |
| GN21 (Bb alone 8 weeks) | Normal |
| IG55 (Bb+Dex) | Normal |
| HH83 (Bb+Mel 8 weeks) | Normal |
| IK20 (control 8 weeks) | Normal |
| GC59 (Bb alone 14 weeks) | Normal |
| GJ23 (Bb+Dex 14 weeks) | Abnormal F waves in tibial nerve from week 2 PI but returned to normal by 8 weeks PI Tibial F waves = 17.2–25.1 at week 2; 16.5–19.6 at week 8 (UL 20.7)∗ |
| GK54 (Bb+Mel 14 weeks) | Abnormal F waves in ulnar and tibial nerves recorded from week 2 PI until end of study Ulnar F waves = 16.3–24.8 (UL 14.8)∗ Tibial F waves = 22.2–33.3 (UL 20.7)∗ |
| HT72 (Bb alone 14 weeks) | Abnormal F waves in median and ulnar nerves recorded from week 2 PI until end of study Median F waves = 15.6–22.7 (UL 14.7)∗ Ulnar F waves = 16.3–23.7 (UL 14.8)∗ |
| GM23 (Bb+Dex 14 weeks) | Normal |
| GN49 (Bb+Mel 14 weeks) | Abnormal F waves in ulnar and tibial nerves recorded from week 2 PI until end of study Ulnar F waves = 15.3–19.6 (UL 14.8)∗ Tibial F waves = 23.4–31.6 (UL 20.7)∗ |
| HT73 (control 14 weeks) | Normal |
Bb, Borrelia burgdorferi; Dex, dexamethasone; Mel, meloxicam; PI, after inoculation UL, upper limit.
UL of normal in controls was based on means + 2 SD. Unless noted, F-wave latencies were below the UL of normal.