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Fate of polyplexes traced for 4 and 10 hours post transfection. Comparison between lipofectamine polyplexes and nuclear targeting polyplexes (6XT) shows similarity and separates from 6XK polyplexes, which contained only endosomal escape functions. 6XK are the polylpexes without nuclear targeting domain, 6XT includes the nuclear targeting domain (TAT) and LTX is commercially available from Invitrogen (Carlsbad, CA).
