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Cytokine production in endothelial cell (EC)–bone marrow–derived macrophage (BMDM) co-culture. CXCL1 (A), monocyte chemotactic protein (MCP-1; B), and IL-6 (C) production during EC co-culture with wild-type (WT) or Mrp14−/− BMDMs. In all cases, cytokine production is significantly greater in EC-WT BMDM co-culture compared with EC-MRP14−/− co-culture. Median and range are shown. ∗∗P < 0.01.
