Medical history by control/exacerbation group. All subjects in subgroup X.

MedDRA preferred term	Exacerbators (n=90) (%)	Non-exacerbators (n=113) (%)	Controls (n=51) (%)
Hypertension	14 (15.6)	18 (15.9)	10 (19.6)
Asthma	4 (4.4)	5 (4.4)	0 (0.0)
Pulmonary tuberculosis	4 (4.4)	0 (0.0)	0 (0.0)
Tuberculosis	4 (4.4)	5 (4.4)	0 (0.0)
Bronchiectasis	3 (3.3)	0 (0.0)	0 (0.0)
Diabetes mellitus	1 (1.1)	4 (3.5)	2 (3.9)
Gout	1 (1.1)	0 (0.0)	0 (0.0)
Hyperthyroidism	1 (1.1)	0 (0.0)	0 (0.0)
Pulmonary bulla	1 (1.1)	0 (0.0)	0 (0.0)
Cor pulmonale	0 (0.0)	1 (0.9)	0 (0.0)
Coronary artery disease	0 (0.0)	1 (0.9)	1 (2.0)