Table 2.
Covariance analysis of repeated measures for creatinine and estimated glomerular filtration rate
| Serum creatinine | eGFR (aMDRD) | |||||
|---|---|---|---|---|---|---|
| Variable | Beta | F | P | Beta | F | P |
| Intercept | 0.9319 | 1.8358 | ||||
| CAV1 genotype | 4.93 | 0.008 | 5.98 | 0.003 | ||
| AA | Reference | Reference | ||||
| AC | 0.0515 | −0.0508 | ||||
| CC | 0.0254 | −0.0310 | ||||
| Time (per year) | 0.0262 | 17.63 | <0.0001 | −0.0298 | 18.23 | <0.0001 |
| Interaction genotype/time (per year) | 3.88 | 0.02 | 3.75 | 0.02 | ||
| AA | Reference | Reference | ||||
| AC | −0.0209 | 0.0230 | ||||
| CC | −0.0219 | 0.0249 | ||||
| Delayed graft function | 0.08 | 0.78 | 0.53 | 0.47 | ||
| No | Reference | Reference | ||||
| Yes | −0.0956 | 0.1322 | ||||
| Interaction genotype/DGF | 6.02 | 0.003 | 6.98 | 0.001 | ||
| AA | Reference | Reference | ||||
| AC | 0.0990 | −0.1287 | ||||
| CC | 0.1691 | −0.2123 | ||||
| Donor age (per year) | 0.0036 | 84.10 | <0.0001 | −0.0045 | 140.76 | <0.0001 |
| Acute rejection | NS | 15.15 | 0.0001 | |||
| No | Reference | |||||
| Yes | −0.0695 | |||||
DGF: delayed graft function, eGFR: estimated glomerular filtration rate, aMDRD: abbreviated modification of diet in renal diseases, NS: not significant.