Table 3.
The relationships between race, IGF1 methylation, and gestational age-adjusted birth weight 1
| IGF1 Methylation 2 | % change in aBW 3 | |||||
|---|---|---|---|---|---|---|
| β | 95% CI | P value | β | 95% CI | P value | |
| Race | ||||||
| Black race | 0.62 | 0.11, 1.12 | 0.02 | −7.45% | −14.44, −0.45 | 0.04 |
| IGF1 methylation | ||||||
| Methylation z-score | - | - | - | −3.32% | −6.17, −0.47 | 0.02 |
| Joint effects | ||||||
| Black race | - | - | - | −5.68% | −12.84, 1.49 | 0.12 |
| Methylation z-score | - | - | - | −2.70% | −5.63, 0.24 | 0.07 |
1Modeled using standard multivariable linear regression; 2 IGF1 methylation z-score controlled for maternal age; 3gestational age-adjusted birth weight (aBW) controlled for maternal age, parity, and infant gender.