Table 3.

Summary of medians, range and statistical comparisons for the Canine Brief Pain Inventory Pain Severity Scores (CBPI PSS) at D0, D14 and D28 of the study

Group	D0	D14	D28	D0 minus D14	Within group change P-value	D0 minus D28	Within group change P-value
NV-01	4.75 (1.75-9.00)	2.00 (0.50-6.25)	2.63 (1.00 – 7.00)	1.50 (-0.75 – 4.50)	0.012	1.50 (-0.75 – 4.00)	0.019
Placebo	3.75 (1.25-8.50)	3.00 (1.00-8.75)	3.00 (1.00 – 8.00)	0.75 (-2.50 – 4.25)	0.164	0.75 (-2.00 – 4.25)	0.347
Between group comparison P-value	0.898	0.719	0.744	0.226		0.210

Decreases in scores signify improvement, and positive values for change indicate improvement. Significant P-values are denoted in bold type.