Scheme 1.
Interaction of 2-ethoxymethylidene-3-oxo esters 1a–c with 5-AT. R = CF3 (a), (CF2)2H (b), Me (c). Conditions, i: TFE, Δ, 32–38 h; ii: Air, rt, 12 days; iii: EtOH, rt, 9 days.
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